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Updated: Sep 9, 2025

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マウスのプライマリベースフィルにおけるIL-3/IL-5/GM-CSF受容体βc信号のTyr573経由でのShcA活性化

Ippei Koshi1, Shigeaki Hida2, Ryuuichi Nishinakamura3

  • 1Department of Molecular and Cellular Immunology, Shinshu University School of Medicine, Matsumoto, Japan.

FEBS letters
|August 29, 2025
PubMed
まとめ

共通のベータ (βc) 受容体のサブユニットは,サイトカイン信号を伝達する. βcのチロシン573は,ShcAを誘導し,インタールイキン-4 (IL-4) 産生とエフェクタ機能を可能にすることが重要です.

キーワード:
IL-3 についてIL-4 についてIL-5 についてショックバソフィール一般的なβ鎖リン酸化生存率

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