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Updated: Sep 9, 2025

Use of a Hanging-weight System for Liver Ischemia in Mice
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Use of a Hanging-weight System for Liver Ischemia in Mice

Published on: August 7, 2012

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MEF2Dは,NAT10との相互作用によってCXCL1を転写的に調節することによって,肝臓の血性不全を悪化させる

Zhigao Deng1, Zhongshan Lu1, Quanwei Cheng1

  • 1Hubei Key Laboratory of Medical Technology on Transplantation, Hubei Provincial Clinical Research Center for Natural Polymer Biological Liver, National Quality Control Center for Donated Organ Procurement, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.

Liver international : official journal of the International Association for the Study of the Liver
|August 29, 2025
PubMed
まとめ

ミオサイト増強因子2D (MEF2D) は,炎症とアポトーシスを促進することによって肝臓不血症再注射損傷 (IRI) を悪化させる. NAT10経由でMEF2Dアセチル化を阻害することは,肝臓IRIに対する潜在的な治療戦略を提供します.

キーワード:
C-X-Cモチーフ・ケモカイン・リガンド 1N-アセチルトランスフェラーゼ10アセチル化肝臓の不全筋細胞増強因子-2Dトランスクリプション

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