関連する実験動画

Updated: Sep 9, 2025

Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches
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Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches

Published on: April 20, 2021

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B細胞受容体体高変異の省略的な広範なモデル

Kevin Sung1, Mackenzie M Johnson1, Will Dumm1

  • 1Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, United States.

eLife
|August 29, 2025
PubMed
まとめ

抗体親和性の成熟を よりよく分析するために 核酸文脈を使用する 身体的ハイパーミューテーション (SHM) の 節約モデルを開発しました これらのモデルは既存の方法よりも優れた性能を提供します.

キーワード:
B細胞受容体コンピュータ生物学折り畳み神経ネットワーク人間免疫学について炎症ソマティック・ハイパーミューテーションシステム生物学

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