日本におけるがん診断後のうつ病と不安症の発生率と時間的傾向:LIFE研究からの洞察

Kengo Kawaguchi^1,2, Megumi Maeda¹, Fumiko Murata¹

¹Department of Health Care Administration and Management, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

International journal of cancer

|August 29, 2025

まとめ

がん患者はしばしば鬱や不安を経験する. 鬱病の発生率は診断後2ヶ月でピークに達し,不安は診断時にピークに達し,メンタルヘルスサポートの重要な時期を強調しました.

科学分野:

腫瘍学
精神科
公衆衛生

背景:

うつ病と不安はがん患者の多くで,治療の順守,生活の質,生存に影響します.
罹患率は知られていますが,がんの診断後のこれらの精神疾患の発生率と時間的な傾向については,さらなる調査が必要です.

研究の目的:

癌の診断後の鬱や不安の発生率と時間的なパターンを判断するためです
うつ病や不安症を発症するリスクが高い患者のサブグループやがんタイプを特定する.

主な方法:

日本の14の自治体で新たに診断された2,863人のクレームデータ (2018年4月~2021年3月) を利用した.
診断後24ヶ月以内にうつ病や不安症と診断された.
生体発生率を計算し,ポアソン回帰を用いて,月間発生率と時間的な傾向を人口統計,治療,癌の種類によって分析した.

主要な成果:

鬱病の総発生率は3. 36/1000人/月,不安症の総発生率は3. 11/1000人/月でした.
鬱病の発生率は診断後約2ヶ月でピークに達し,不安症の発生率は診断された月にピークに達した.
女性,化学療法を受けている患者,および臓がん患者ではより高い発症率が観察されました.

結論:

鬱や不安の発生度やタイミングは癌の診断後に大きく変化します
特定の患者グループ (女性,化学療法を受けた患者) とがんタイプ (臓) はリスクが高い.
発見は,がん患者にとって高リスク期間の間に間に合わせた精神衛生介入の必要性を強調しています.

キーワード:

心配する癌の診断うつ病現実世界のデータ

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