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Updated: Sep 9, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

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TGF-β阻害剤SB431542は,マルチステップ阻害によってSARS-CoV-2の複製を抑制する

Assim Verma1, Himanshu Kamboj1,2, Garvit Kumar1

  • 1National Centre for Veterinary Type Cultures, ICAR-National Research Centre on Equines, Hisar, India.

Journal of virology
|August 29, 2025
PubMed
まとめ

TGF-β受容体阻害剤であるSB431542は,ウイルスの侵入,集合,放出を標的として,SARS-CoV-2に対する強力な広範囲の抗ウイルス活性を示しています. 重要なことに,SARS-CoV-2は50世代後に耐性を発達させず,現在の抗ウイルス薬に比べて有意な利点をもたらしました.

キーワード:
SARS-CoV-2についてウイルス対策

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