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Updated: Sep 9, 2025

Visualization of Replisome Encounters with an Antigen Tagged Blocking Lesion
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Published on: July 27, 2021

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抗変異性活性を持つ二重メカニズム抗菌ペプチドは,レプリソームを標的とし,細胞包膜のストレスを引き起こす

Amanda Holstad Singleton1, Olaug Elisabeth Torheim Bergum1, Jana Scheffold1

  • 1Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

mSphere
|August 29, 2025
PubMed
まとめ

新しいペプチド抗生物質であるBTP-001は,細胞膜とDNA複製を破壊することで,多剤耐性細菌に効果的に抵抗します. 抗菌剤耐性の増大に対して 望ましい新しい治療戦略を提供する ユニークな二重作用機構です

キーワード:
APIM についてエシェリキア・コライ抗変異剤細胞に浸透するペプチドプロテオミクストランスクリプトミクスβ-クランプ

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