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Updated: Sep 9, 2025

Mouse Fetal Liver Culture System to Dissect Target Gene Functions at the Early and Late Stages of Terminal Erythropoiesis
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Mouse Fetal Liver Culture System to Dissect Target Gene Functions at the Early and Late Stages of Terminal Erythropoiesis

Published on: September 9, 2014

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EPAS1変異性先天性赤血球症における標的型HIF-2α阻害の成功

Elliot Ensink1, Tobias Else2, Mark Hannibal3

  • 1College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, USA.

Pediatric blood & cancer
|August 29, 2025
PubMed
まとめ

新しい治療法であるベルツチファンは,EPAS1変異の11歳の患者に多細胞症を効果的に治療しました. この低酸素誘導因子2α阻害剤はヘモグロビンレベルを正常化し,新しい治療戦略を提供しました.

キーワード:
低酸素誘導因子2α (HIF-2α) ポリシテミア

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