新型アンジオテンシン変換酵素とジジフスジューバペプチドKALVAPのディペプチジルペプチダゼIV阻害ペプチドの設計と実験検証

Huan Wen1, Jing Lan1, Kuo Dang1

  • 1College of Food Science and Engineering, Ningbo University, Ningbo, China.

まとめ

改造されたペプチドWALVAPとWPLVAPは,KALVAPと比較して,ディペプチジルペプチダゼ (DPP) -IV抑制活性が著しく強化されています. これらの新しいペプチドは,グルコース代謝とインスリン分泌を改善し,糖尿病と高血圧の薬剤候補の可能性を示しています.

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