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Updated: Sep 9, 2025

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
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m7GライターのMETTL1とBUD23の過剰発現は,腎臓のクリア細胞癌において腫瘍性をもたらす

Anni Su1,2, Jessica Tieng1,2, Xueying S Xu2

  • 1Epigenetics and RNA Biology Laboratory, Charles Perkins Centre, University of Sydney, Camperdown, Australia.

The Journal of pathology
|August 29, 2025
PubMed
まとめ

N7-メチルグアノシン (m7G) レーターであるMETTL1とBUD23は腎臓がんで過剰発現し,腫瘍の成長を誘導する. これらのm7Gライターをターゲットにすることで,腎臓のクリア細胞癌 (KIRC) の新しい治療戦略を提供することができる.

キーワード:
BUD23METTL1 についてRNAの改変腎臓がんm7G メチル化腫瘍遺伝子腫瘍抑制遺伝子

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