パーメトリンは,Litopenaeus vannameiの抗酸化防御反応を妨害する
Juliana Righetto Moser1, Eliziane Silva1, Maria Risoleta Freire Marques1
1Laboratório de Biomarcadores de Contaminação Aquática e Imunoquímica - LABCAI, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina - UFSC, Florianópolis, SC, Brazil.
Xenobiotica; the fate of foreign compounds in biological systems
|August 29, 2025
まとめ
パーメトリンは,養殖エビ (Litopenaeus vannamei) の抗酸化防御と酵素活性に干渉する. この殺虫剤は水生生物に危険をもたらし,それに曝露されたエビの重要な生物学的プロセスに影響を与えます.
科学分野:
- 環境毒理学
- 水中の毒性学
- 農薬 が 水 の 生物 に 与える 影響
背景:
- ペルメトリンは農業で広く使用されるピレトロイド殺虫剤である.
- 農薬は非標的水生生物に悪影響を及ぼす可能性があります.
- 養殖のエビ (Litopenaeus vannamei) は環境汚染に脆弱である
研究 の 目的:
- ペルメトリンが養殖エビに与える毒性の研究
- エビの酵素抗酸化防御反応に対するパーメトリンの影響を評価する.
- パーメトリンの第2相生物変異とアセチルコリネステラーゼ活性への影響を評価する.
主な方法:
- 養殖エビ (Litopenaeus vannamei) のパーメトリンの暴露
- と肝臓の酵素抗酸化防御反応の測定
- グラタチオンS-トランスファーゼ (GST) の第2相生物変異の活性測定
- アセチルコレネステラス (AchE) の活性に関する評価
主要な成果:
- ペルメトリンの曝露は,エビのと肝臓の酵素抗酸化防御反応を妨げました.
- グラタチオンS- トランスファーゼ (GST) 活性によって示される第2段階の生物変換が影響を受けた.
- アセチルコリネステラーゼ (AchE) の活性も,パーメトリンの暴露によって影響を受けた.
結論:
- パーメトリンはリトペネウス・ヴァナメイ (Litopenaeus vannamei) の養殖エビに毒性効果を発揮する.
- 抗酸化防御と酵素活動に障害が生じると この殺虫剤に対するエビの脆弱性が明らかになります
- ペルメトリンは水生生態系とその住民に 危険をもたらします
関連する概念動画
The Electron Transport Chain
13.8K
The electron transport chain or oxidative phosphorylation is an exothermic process in which free energy released during electron transfer reactions is coupled to ATP synthesis. This process is a significant source of energy in aerobic cells, and therefore inhibitors of the electron transport chain can be detrimental to the cell's metabolic processes.
Inhibitors of the electron transport chain
Rotenone, a widely used pesticide, prevents electron transfer from Fe-S cluster to ubiquinone or Q...
Inhibitors of the electron transport chain
Rotenone, a widely used pesticide, prevents electron transfer from Fe-S cluster to ubiquinone or Q...
13.8K
Necrosis
5.3K
Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
5.3K
Radical Autoxidation
2.5K
The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
2.5K
Oxygen Requirements and Growth Patterns
2.6K
Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...
2.6K
Microbial Bioremediation of Pesticides
96
Pesticides often feature structurally complex chemical architectures, incorporating halogen groups and multiple aromatic rings. These characteristics confer high chemical stability, rendering many pesticides resistant to natural degradation processes. This resistance poses significant environmental concerns, as persistent pesticide residues can accumulate in ecosystems and affect non-target organisms.Despite the inherent stability of many pesticides, certain microorganisms possess the metabolic...
96


