南アジア の 血栓性 心臓 病 の 性別 の 差異: 食事 習慣 の 影響
Tania Rahaman1, Edina Cenko1, Olivia Manfrini2
1Department of Medical and Surgical Sciences, University of Bologna, Italy.
JACC. Asia
|August 29, 2025
まとめ
南アジアでは心臓病による死亡率が高く,パキスタンでは男女差が大きい. 高血圧と栄養不良は 女性のIHD死亡の主な危険因子です
科学分野:
- 心臓病と公衆衛生
- 流行病学
- 世界保健
背景:
- 南アジアは心臓発作症 (IHD) の 世界最大の負担に直面しています.
- 性別,収入,国によってIHDの結果の変動を理解することは公衆衛生にとって極めて重要です.
- IHDの流行と死亡率の性別特有の傾向は,詳細な分析を必要とする.
研究 の 目的:
- 南アジア全域のIHDの罹患率と死亡率の性別特有の傾向を分析する.
- 地域における男性と女性のIHD結果の違いを特定する.
- IHDの標的型公衆衛生介入の情報提供
主な方法:
- 世界疾病負担 (GBD) データ (2005年-2021年) の横断分析
- 南アジア5か国におけるIHDの年齢標準化死亡率 (ASMR) と流行率 (ASPR) の推定.
- Zスコアを用いたASMR-ASPR指数と性別比較の計算
主要な成果:
- 男性は一貫して女性よりも高いIHDASMRを示した.
- パキスタンは男性に比べてASMRとASPRの比率が高く,死亡リスクが高いことを示した.
- ブータンとパキスタンでは,女性に対するIHD死亡リスク因子 (例えば,高血圧,低野菜/繊維摂取量) の違いが確認された.
結論:
- IHDの死亡率は南アジアでは依然として重大な公衆衛生問題です.
- IHDの結果における性別の格差はパキスタンで最も顕著です.
- 高血圧と 野菜と繊維の少ない摂取は 女性におけるIHD死亡の 重要な危険因子です
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