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Updated: Sep 9, 2025

Chemogenetic Regulation in Reprogrammed Stem Cell-derived Precursor Cells in Treating Neurodegenerative Diseases
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神経学的障害に対する選択的モノアミン酸化酵素B阻害剤の識別のための薬物再利用アプローチの導入: in Silicoおよびin vitroアプローチ

Mohamed Mohany1,2, Salim S Al-Rejaie1, M Arockia Babu3

  • 1Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.

Journal of computer-aided molecular design
|August 29, 2025
PubMed
まとめ

この研究では,神経疾患に対する新しいMAO-B阻害剤を見つけるために,既存の薬物を再利用しました. バゼドキシフェンとエピカテキンは有望な選択的MAO- B阻害を示し,潜在的な治療用途を示唆した.

キーワード:
アルツハイマー病薬物の再利用MAO-B 阻害剤神経障害パーキンソン病

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