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Updated: May 7, 2026

Using Click Chemistry to Measure the Effect of Viral Infection on Host-Cell RNA Synthesis
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エチニルウリジンラベリングによる呼吸器シンチチアルウイルスRNA合成部位の可視化

Risso-Ballester J1, Rincheval V2, Marie-Anne Rameix-Welti3

  • 1Institute of Virology, School of Medicine, Technical University of Munich, Munich, Germany.

Methods in molecular biology (Clifton, N.J.)
|August 29, 2025
PubMed
まとめ

5-エチニルウリジン (5-EU) とクリック化学を用いた代謝RNAの標識は,新たに合成されたウイルスRNAを可視化します. これは,ウイルスのRNA合成がインクルージョンボディ (現在ではウイルス工場と呼ばれている) の内部で,呼吸器系シンチチアルウイルスに感染した細胞で発生することを確認しています.

キーワード:
5-エチニルリジン (EU)包摂機関 (IB)新生ウイルスRNAとクリック化学RNA合成呼吸器同胞ウイルス (RSV)

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