シンガポールの EQ-5D-5L 値セットの開発
Nan Luo1, Annushiah Vasan Thakumar2, Ling Jie Cheng3,4,5
1Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore. ephln@nus.edu.sg.
PharmacoEconomics
|August 29, 2025
まとめ
シンガポールの新しいEQ-5D-5L値セットは,複合時間トレードオフ法を使用して開発されました. このツールは -0.851から1,000までのシンガポールの健康上の好みを反映しています
科学分野:
- 健康 経済
- サイコメトリクス
- 生活の質に関する研究
背景:
- EQ-5D-5Lは,医療技術の評価のために広く使用されているマルチアトリビュートユーティリティのツールです.
- 地域特有の価値セットの開発は,正確な健康結果評価に不可欠です.
研究 の 目的:
- シンガポールの住民に合わせた EQ-5D-5L 値セットを開発する.
- シンガポールの健康評価のための標準化されたツールを提供すること.
主な方法:
- EuroQol 研究財団の評価プロトコルの"軽量版"が使用されました.
- 複合的な時間トレードオフ (cTTO) 任務は,配当サンプルに含まれるシンガポールの住民500人に管理されました.
- クロス・バリデーションは,すべての3,125のEQ-5D-5L健康状態を評価するための最適なモデルを特定しました.
主要な成果:
- 2つの双方向の相互作用項を備えた20パラメータのメイン効果モデルは優れたパフォーマンスを示しました.
- 結果として得られた値は -0.851 (最悪の健康状態) から 1,000 (最良の健康状態) に及ぶ.
- 痛み/不快感と不安/うつ病の次元は,使用不便に最も大きく貢献しました.
結論:
- シンガポールの新しいEQ-5D-5L値セットが開発されました.
- この値セットは,シンガポールの EQ-5D-5L ユーザーに推奨されます.
- 健康状態の評価における相互作用効果と非線形性に関するさらなる研究が奨励されます.
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