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Updated: Sep 9, 2025

A High-throughput Cre-Lox Activated Viral Membrane Fusion Assay to Identify Inhibitors of HIV-1 Viral Membrane Fusion
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A High-throughput Cre-Lox Activated Viral Membrane Fusion Assay to Identify Inhibitors of HIV-1 Viral Membrane Fusion

Published on: August 14, 2018

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コレステロールがGP41誘発のHIV膜融合に及ぼす影響の調査

Jatin Soni1, Taraknath Mandal1

  • 1Department of Physics, Indian Institute of Technology Kanpur, Kanpur 208016, India.

Journal of chemical theory and computation
|August 29, 2025
PubMed
まとめ

コレステロールは,ヒト免疫不全ウイルス (HIV) 感染において,宿主細胞とのウイルスの封筒融合を助長することで,二重の役割を果たします. この研究では コレステロールがHIVの侵入を促し 抗ウイルス薬の標的となる可能性を明らかにしました

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