2型糖尿病のインドネシア人成人の糖尿病性網膜症および失明の発生および進行
Muhammad Bayu Sasongko1, Gandhi Anandika Febryanto1, Supanji Haryanto1
1Department of Ophthalmology, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada - Dr. Sardjito General Hospital, Yogyakarta, Indonesia.
PloS one
|August 29, 2025
まとめ
糖尿病性網膜症 (DR) の発生率と進行は,2型糖尿病のインドネシア人成人に研究されました. 糖尿病の持続期間が長くなった場合,DRと視力を脅かすDR (VTDR) の発症リスクが著しく増加しました.
科学分野:
- 眼科について
- 内分泌学
- 公衆衛生
背景:
- 糖尿病性網膜症 (DR) は,予防可能な失明の主な原因です.
- インドネシア の 成人 人口 の 大部分 に 2 型 糖尿病 が 感染 し て い ます.
- DRの発生と進行を把握することは公衆衛生の介入において極めて重要です.
研究 の 目的:
- 糖尿病性網膜症 (DR) と失明の発生率と進行率を決定する.
- 2型糖尿病のインドネシア人成人のDRと失明に関連した危険因子を特定する.
主な方法:
- 2型糖尿病を有する30歳以上の899人の前向きなコホート研究.
- 標準化された臨床検査と眼鏡検査,双フィールド網膜撮影
- DRはマスクされた格レーダーによって格付けされ,分類には非増殖性DR (NPDR),増殖性DR (PDR),および視力を脅かすDR (VTDR) が含まれていた.
主要な成果:
- DRとVTDRの発生率は,それぞれ1000人当たり34. 6と24. 5でした.
- 糖尿病の持続期間が長くなった場合,5年以内にDR (HR 1.37) とVTDR (HR 2. 00) が発症し,DR (HR 1. 50) が進行するリスクが増加しました.
- 肥満,ガングレナ,神経病はDRの危険性や進行と関連しており,農村での生活は失明の危険性を高めました.
結論:
- インドネシアの2型糖尿病患者のDR,VTDR,失明の報告された発生率と進行率.
- 5年以内にDRとVTDRの発症の重要な危険因子です.
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