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Updated: Sep 9, 2025

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR
09:37

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR

Published on: February 12, 2019

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ダイナミックな核極化核磁気共振光譜を用いたヒドロキシプロピルメチルセルロースアセチルサクシネートのスペクトル割り当てと置換物の分布

Ronan P Cosquer1, Arthur C Pinon2, Mária Šoltésová2

  • 1Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, U.K.

Molecular pharmaceutics
|August 29, 2025
PubMed
まとめ

この研究は,無形固体分散 (ASD) の主要なポリマーであるヒドロキシプロピルメチルセルロースアセチルサクシネート (HPMC-AS) の構造を明らかにする. 新しいNMR方法により,その置換剤の分布が確認され,ASDにおける薬物安定化の理解が改善されました.

キーワード:
カーボンの接続性ダイナミックな核極化ハイドロキシプロピルメチルセルロースアセチルサクシネート置換体分布について

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