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Updated: Jul 30, 2026

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    Proceedings of the National Academy of Sciences of the United States of America
    |August 29, 2025
    PubMed
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    No abstract available in PubMed .

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    Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

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    The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
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