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Updated: Sep 9, 2025

Measuring RAN Peptide Toxicity in C. elegans
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m6Aは,CAGの繰り返し拡張RNAからのRAN変換を調節する

Yuxiang Sun1,2, Zhouxian Li1, Hui Dai1

  • 1Department of Chemistry, University of California Riverside, Riverside, CA 92521-0403.

Aggregate (Hoboken, N.J.)
|August 29, 2025
PubMed
まとめ

メチル化 (m6A) は,スピノセレベラ性アタキア3型 (SCA3) の拡張CAGリピートからのリピート関連非AUG (RAN) 変換を促進する. METTL3はこのプロセスを促進し,FTOはメチル化マークを削除し,RAN変換製品に影響を与えます.

キーワード:
CAGの再拡大N6-メチラデノシンRANの翻訳

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