東アジアと中国における1990年から2021年までの青少年における疾患負担と痛風の傾向:2021年世界疾病負担調査の結果
Lu Yang1, Zhenyu Wang1, Ligang Cui1
1Peking University Third Hospital, Haidian, China.
Frontiers in public health
|August 29, 2025
まとめ
青少年の痛風は 世界的に増加しています 特に東アジアと中国では ライフスタイルの変化と 代謝リスクが原因です 女性の負担は高くなっており,2050年までに増加する罹患率に対処するために 標的を絞った介入が必要となります
科学分野:
- メタボリック障害
- 流行病学
- 青少年 の 健康
背景:
- 尿酸結晶の堆積による代謝障害である痛風は,特に東アジアと中国では,青少年にあまり研究されていません.
- これらの地域における 痛風の発生率の上昇は 食事と経済の大きな変化と相関しています
- この研究では,1990年から2021年までの青少年の痛風のグローバル,東アジア,中国の負担を対象に,2050年まで予測しています.
研究 の 目的:
- 青少年における痛風のグローバル,東アジア,中国の負担を評価するためです.
- 発症率,罹患率,障害調整寿命年数 (DALYs) の傾向を分析する.
- 将来の傾向を予測し,主要なリスク要因を特定する.
主な方法:
- 青少年 (10歳から19歳) の2021年のグローバル・バード・オブ・ディジーズ (GBD) のデータを使用した.
- 年齢標準化率 (ASR) と年率変動率 (EAPC) を計算した.
- SDI-DALY協会の予測とスムージングスプリンのためにARIMAモデルを使用し,性別と地域によって定量化されたリスク要因.
主要な成果:
- 痛風の発生率,罹患率,およびDALYのグローバルASRは1990年から2021年にかけて毎年増加しました.
- 東アジアはより急激に増加し,台湾 (中国の州) が最も高い割合を報告した.
- 中国の負担は代謝リスク,肥満,腎臓機能不全によって著しく増加しました.
結論:
- 東アジアと中国では 青少年における痛風の拡大は 肥満,代謝症候群,生活習慣の変化と関連しています
- 性差は女性のリスクが 認識されていないことを示しています
- 予測される増加を抑制するには,変更可能なリスクとジェンダー特有の戦略を対象とした早期の介入が不可欠です.
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