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機能的上部胃腸疾患における小腸の細菌過剰増殖の調査:包括的な症例対照研究
Bhaswati C Acharyya1,2, Meghdeep Mukhopadhyay1
1Department of Pediatric Gastroenterology and Hepatology, Institute of Child Health, Kolkata 700017, West Bengal, India.
World journal of clinical pediatrics
|August 29, 2025
まとめ
小腸の細菌過剰成長 (SIBO) は,原因不明の上部胃腸の症状を持つ子供において一般的です. これらの小児患者のSIBOの調査は,正常な内視鏡検査結果であっても推奨されます.
科学分野:
- 小児胃腸内科
- 微生物群の研究
- 診断 の 正確 さ
背景:
- 小腸の細菌過剰増殖 (SIBO) は,機能的胃腸疾患で頻繁に疑われる.
- 胃腸上部に症状がある子どもは,SIBO検査を受けないことが多い.
研究 の 目的:
- 機能的な上部消化器系の症状を持つ子供におけるSIBOの流行を決定する.
- 内視鏡の病変とない子供のSIBO状態を比較する.
主な方法:
- 129人の上部腸内症候群の小児 (6~18歳) は,陽子ポンプ阻害薬 (PPI) を服用する前に内視鏡検査を受けた.
- 症例は内視鏡検査で正常で,対照群は内視鏡検査で損傷を受けた.
- グルコースと水素の呼吸検査は,両方のグループでSIBOを診断しました.
主要な成果:
- SIBOは,正常な内視鏡検査 (症例) を受けた子供の59%で,病変 (対照群) を受けた子供の21%で診断された.
- 症例におけるSIBOの確率比は5. 38で,有意な関連性を示した.
- 吐き気,口臭,胃の充満は,小児におけるSIBOを予測した.
結論:
- SIBO検査は,内視鏡で説明できない上部消化器系の症状を持つ子供にとって有益です.
- SIBOの早期診断と治療は,小児の消化器官の健康状態を改善することができます.
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