妊娠中のHIV薬への曝露は,成人ラットの子孫における腸内粘膜に関連する微生物の多様性を変化させる

Yaswanthi Yanamadala1, Chandra Mohan Reddy Muthumula1, Kuppan Gokulan1

  • 1Division of Microbiology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States.

まとめ

抗レトロウイルス治療 (ABC/ DTG/ 3TC) の周産期曝露は,老鼠の腸内細菌を変化させる. この薬の組み合わせは腸内粘膜に関連する微生物に影響し,効果は性別と用量によって異なります.

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