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Updated: Sep 9, 2025

Optimized Griess Reaction for UV-Vis and Naked-eye Determination of Anti-malarial Primaquine
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マラリアボックス MMV008138のベンゾリング改変:抗マラリア効果と微小体安定性への影響

Maryam Ghavami1, Haibo Li1, Lixuan Liu1

  • 1Department of Chemistry and Virginia Tech Center for Drug Discovery, Virginia Tech 1040 Drillfield Drive Blacksburg VA 24061 USA.

RSC medicinal chemistry
|August 29, 2025
PubMed
まとめ

テトラヒドロ-β-カルボリン1の誘導体は,抗マラリア活性を改善するために合成されました. 1つのアナログはよりよい代謝安定性を示したが,マラリアに対する経口有効性を高めなかった.

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