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Updated: Sep 9, 2025

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
09:37

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging

Published on: July 14, 2016

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コストマン症候群に起因するHAX1遺伝子は,JAM1の細胞内輸送を通じて,歯周皮質のバリア機能を調節する

Keita Tanigaki1, Tsukasa Tamamori1, Naoko Sasaki2

  • 1Department of Preventive Dentistry, Graduate School of Dentistry, The Osaka University, Osaka, Japan.

Frontiers in cell and developmental biology
|August 29, 2025
PubMed
まとめ

コストマン症候群はHAX1遺伝子変異と関連しており,JAM1発現の低下により歯周炎を引き起こす. 感染感受性が高まります.

キーワード:
HAX1 についてJAM1 についてコストマン症候群ポルフィロモナス・ジンギヴァリス抗がん剤バリアシスプラチン歯周病

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