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Updated: Sep 9, 2025

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

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ブリッジされたアゾベンゼンは,G-四重複DNA/二重複結合に完全に可逆的な光制御結合を示している

Javier Ramos-Soriano1, Y Jennifer Jiang1, Bowen Deng1,2

  • 1School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.

JACS Au
|August 29, 2025
PubMed
まとめ

研究者らは,HIV-1 LTR-III G-quadruplex (G4) のような特定のDNA構造に選択的に結合する光制御分子を開発しました. この突破は,潜在的なナノデバイスの適用のために可視光を用いたDNA結合の可逆制御を可能にします.

キーワード:
DNAナノデバイスG4 / デュプレックスDNAジャンクションアゾベンゼンフォトスイッチ超分子DNAの相互作用

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