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Updated: Sep 9, 2025

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PKMζは空間記憶の再統合を駆動するが,維持はしない

João Rodrigo de Oliveira1, Janine I Rossato1, Johseph P G Souza1

  • 1Memory Research Laboratory, Brain Institute, UFRN, Natal, Brazil.

Frontiers in synaptic neuroscience
|August 29, 2025
PubMed
まとめ

タンパク質キナーゼMゼタ (PKMζ) は,モリス水迷路 (MWM) の空間記憶の再統合に不可欠です. 記憶の再活性化後にPKMζを阻害すると,ラットでは長期間の記憶喪失を引き起こします.

キーワード:
PKMζ記憶喪失ヒッポカンプスメモリ維持再統合空間記憶

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