薬剤師によるヒト免疫不全ウイルス (HIV) 暴露前予防 (PrEP) の実施と承認
Mackenzie d'Entremont-Harris1, Tasha Diana Ramsey1,2, Kathleen MacNabb1
1Pharmacy Department, Nova Scotia Health, Halifax, NS.
まとめ
薬剤師が指導するHIVの暴露前予防療法 (PrEP) は高リスクの個人に有効で受け入れられます. 薬剤師がPrEPを処方することを許可する 規制の変更につながりました
科学分野:
- 薬理学について
- 公衆衛生
- 感染症
背景:
- 暴露前予防 (PrEP) は非常に効果的なHIV予防戦略です.
- PrEPの不足は 処方箋の入手が 限られていることによるものです
- この研究は,薬剤師によるPrEPの利用の改善の必要性を明らかにしています.
研究 の 目的:
- 薬剤師によるPrEP管理が臨床的結果と受容性に与える影響を評価する.
- 薬剤師によるPrEPの処方とモニタリングの有効性を評価する.
- 薬剤師が管理する PrEP サービスの患者の受容性を決定する.
主な方法:
- 薬剤師主導のPrEP管理は6ヶ月間にわたって10の地域薬局で実施されました.
- 最初の処方箋と再処方箋の 処方箋プロトコルを使用しました
- 医療介入の理論的枠組みを用いて患者の受容性を評価した.
主要な成果:
- 37人の参加者が研究を完了し,その半分はPrEPを初めて使用していた.
- 全ての参加者は男性とセックスする男性や トランスジェンダーの女性でした
- 患者の受け入れ率が高く,プライバシーや汚名に関する懸念はなかった.
- すべての参加者はHIV陰性であり,共感染者は治療に関連していた.
結論:
- 薬剤師によるPrEP管理は 高いリスクの患者に受け入れられる 効果的なサービスです
- このモデルは, PrEP を取得するための別の経路を提供します.
- この研究は,ノバ・スコシアで薬剤師が PrEP を処方することを許可する規制の変更に寄与しました.
関連する概念動画
01:10Retrovirus Life Cycles
46.8K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
46.8K
01:19Pharmacovigilance
983
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
983
01:26Drug Administration and Therapy Phases: Overview
738
Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
738
01:02Prescription, Nonprescription and Orphan Drugs
842
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
842
01:15Drug Dosage Regimen: Overview
3.8K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
3.8K
01:17Healthcare Agencies II
749
There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
749