慢性腎臓病患者の薬剤の安全性向上と高リスク薬剤の処方:検証研究
Katie Halliday1, Natalie Ratajczak1, Marisa Battistella2,3
1Faculty of Health, College of Pharmacy, Department of Medicine, Dalhousie University, Halifax, NS.
まとめ
慢性腎臓病 (CKD) の患者の薬剤投与を最適化するために,コミュニティの薬剤師は現在,検証されたツールキットを使用し,安全性とケアを改善することができます.
科学分野:
- 薬理学について
- 腎臓科
- 医療情報学
背景:
- 慢性腎臓病 (CKD) はカナダ人の10人に1人に影響し,慎重に薬剤管理を必要とする.
- 腎臓で排出される誤用薬は,慢性腎臓病の患者に重大なリスクをもたらす.
- 不一致した薬の供給は 慢性腎臓病の治療薬の投与量を最適化するために コミュニティの薬剤師に挑戦しています
研究 の 目的:
- コミュニティの薬剤師のための薬剤ツールキットと意思決定支援アルゴリズムを開発し,検証する.
- 慢性腎臓病の患者に高リスクの薬を安全かつ効果的に処方することを強化する.
- 慢性腎臓病の患者に対して 薬剤師が使用する薬剤資源の不一致を解決する.
主な方法:
- 51のツールキットとアルゴリズムが Lynnの方法によって開発されました.
- 内容と顔の妥当性は,チーム専門家とコミュニティの薬剤師によって,アンケートとインタビューによって評価されました.
- 検証には,コンテンツの有効性指数 (I-CVI,S-CVI/Ave) と顔の有効性測定値を含む複数のラウンドが含まれていました.
主要な成果:
- 38の薬剤のツールキットは高濃度で 専門家とコミュニティの薬剤師の検証後に有効性を獲得しました
- 内容の妥当性指数 (I-CVI,S-CVI/Ave) と顔の妥当性パーセントは,事前に指定された値を満たしているか,または超えている.
- 検証プロセスには 22人のチーム専門家と 23人のコミュニティ製薬師が複数回に参加しました.
結論:
- 開発されたツールキットとアルゴリズムは,コミュニティの薬局の実践に高い内容と有効性を示しています.
- これらの検証されたリソースは,CKD患者の薬剤管理を最適化するために薬剤師を支援することができます.
- 将来の研究は,これらのツールキットを実際の効果と安全性の評価のためのデジタルプラットフォームに統合することに焦点を当てます.
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