甲状腺がんの負担とアジアにおける国家開発レベルとの関連:47カ国の証拠 (1990-2021年)
Wenyi Qin1,2, Jiong Lin2, Zhi Zhang2
1Faculty of Chinese Medicine, Macau University of Science and Technology, Macau, Macau SAR, China.
Frontiers in oncology
|August 29, 2025
まとめ
甲状腺がんの発生率は 世界的に特にアジアで 増加しており 国の発展と相関しています しかし 医療の改善により 長期的に生存率が向上しています
科学分野:
- 腫瘍学
- 流行病学について
- 世界保健
背景:
- 甲状腺がんの発生率と死亡率は,世界的に顕著に変化しています.
- 甲状腺がんの傾向に対する国の発展の影響を理解することは,公衆衛生戦略にとって極めて重要です.
研究 の 目的:
- 1990年から2021年までの甲状腺がんの発生率と死亡率の世界的傾向を調べる.
- 国家開発指標と甲状腺癌の負担の関係を探求する.
主な方法:
- 47か国 (1990年−2021年) の2011年世界疾病負担調査のデータを活用した.
- 人力開発指数 (HDI),社会進歩指数 (SPI),栄養と医療 (NMC),医師の密度 (DOD),個人医療費 (PHS) を用いて国の発展を評価した.
- 分散図表,熱図,主要成分分析 (PCA) を用いて相関分析を行い,生存率の評価には死亡率対発生率 (MIR) を用いた.
主要な成果:
- 甲状腺がんによる世界的な死亡率は1990年の21,893人から2021年の44,798人に増加し,2021年にはアジアが62.8%を占めた.
- 発症率は10万人に1. 41から3. 36に増加し,特に男性ではHDI,SPI,NMCと正の相関関係を示した.
- 死亡率はHDI,NMC,PHSと負の相関を示し,全般的なMIRは減少し,生存率が改善されたことを示した.
結論:
- 甲状腺 がん の 発生 率 が 増加 し て いる の は,特に 発展 し た アジア 諸国 で,世界 的 に 増加 し て いる の です.
- 発症率が上昇しているにも関わらず 予測の改善と医療へのアクセスが 世界的に生存率の向上につながっています
さらに関連する動画
06:08Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
Published on: June 2, 2023
1.9K
05:41Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
730
関連する概念動画
Synthesis and Regulation of Thyroid Hormones
5.1K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
5.1K
Functions of Thyroid Hormones
3.1K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
3.1K
The Thyroid Gland
4.3K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
4.3K
Cancer Survival Analysis
448
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
448
Cancer Prevention
6.3K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.3K
Prevalence and Incidence
790
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
790
