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Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents01:24

Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents

684
In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
684
Drugs for Peptic Ulcer Disease: Prostaglandin Analogs as Mucosal Protective Agents01:20

Drugs for Peptic Ulcer Disease: Prostaglandin Analogs as Mucosal Protective Agents

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The gastric mucosa produces prostaglandins E2 (PGE2) and prostacyclin (PGI2), crucial in maintaining gastric health. They exert cytoprotective effects, including increasing bicarbonate secretion, releasing protective mucin, reducing gastric acid output, and preventing harmful vasoconstriction. These effects are mediated through various receptors, such as EP1, EP2, EP3, and EP4.
Non-steroidal anti-inflammatory drugs (NSAIDs) can induce peptic ulcers by inhibiting cyclooxygenase, decreasing...
595

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口腔粘膜炎の治療における予防的自己生物調節:高リスク症例研究

Joseph Ryan1, Lee Na Chong2,3,4, Robert Jared Dunn4

  • 1School of Rural Medicine, Charles Sturt University, Orange, NSW, Australia.

Case reports in oncology
|August 29, 2025
PubMed
まとめ
この要約は機械生成です。

904nmおよび600nmレーザーを用いた予防的光バイオモダレーション (PBM) は,高リスクがん患者の口腔粘膜炎の重症度を効果的に軽減しました. このアプローチは,抗腫瘍療法中に生活の質を向上させる可能性を示しています.

科学分野:

  • 腫瘍学
  • 生物医学工学
  • レーザー療法

背景:

  • 口腔粘膜炎 (OM) は,化学放射線治療のような癌治療の弱体化副作用です.
  • 赤と近赤外線を用いた光生物調節 (PBM) は,OMにとって有望な介入です.
  • 最適なPBMのタイミングと投与方法については,さらなる調査が必要です.
キーワード:
ケースレポート頭頸部 がん口腔粘膜炎光バイオモジュレーション口内炎

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