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Updated: Sep 9, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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CLK2 KEAP1/NRF2とp53経路を調節し,大腸がんにおけるフェロプトーシスを抑制する

Hai-Meng Zhou1, Yi Liu2, Feng Shi2

  • 1Wuhan University, Wuhan, Hubei, China.

Cancer research
|August 29, 2025
PubMed
まとめ

CLK2は,KEAP1/NRF2/HMOX1およびp53/SLC7A11経路を調節することにより,結腸直腸がん (CRC) のフェロプトーシスを抑制する. CLK2をターゲットにすると,フェロプトーシスとCRCの治療効果が向上する可能性があります.

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