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Updated: Sep 9, 2025

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

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乳がん治療における金属リガンドによるCOX-2標的Ru-arene複合体のシネジスティック強化戦略

Guan-Dong Zhang1, Wei Hao2, Zheng-Hong Yu2

  • 1Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Nanjing Drum Tower Hospital, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.

Journal of inorganic biochemistry
|August 29, 2025
PubMed
まとめ

新しいルテニウム複合体であるRu-tolは,COX-2を阻害し,細胞死を誘発することで,トリプルネガティブ乳がん (TNBC) を効果的に標的にします. このメタル・リガンドの シネジスティック・エンハンスメント戦略は 新型TNBCの治療法の開発に 期待を寄せています

キーワード:
抗転移と抗侵入剤COX-2 についてメタル・リガンドのシナジスティック強化戦略ルアレン複合体トリプルネガティブ乳がん

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Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies09:29

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A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions07:40

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions

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