幼児期の不良体験と予期せぬ妊娠との関連:体系的なレビューとメタ解析
Xiaoxue Li1, Boran Yang2, Lirong Nie2
1Cangzhou City Center for Disease Prevention and Control, Cangzhou City, Hebei Province, China.
Child abuse & neglect
|August 29, 2025
まとめ
予期せぬ妊娠 (UP) のリスクは,投与量-反応によって著しく増加します. 子どもの保護,精神的健康,生殖ケアに関する早期の介入は,長期的な健康上の影響を軽減するために不可欠です.
科学分野:
- 公衆衛生
- 心理学
- 社会学
背景:
- 不一致な研究結果では,不良な子供時代体験 (ACE) と未計画妊娠 (UP) が関連しています.
- 試料の特性や測定方法の変動は不一致な結果をもたらします.
- ACEsとUPの関係を明らかにするために,包括的なメタ分析が必要である.
研究 の 目的:
- ACEサブタイプとUPの関連性を評価する.
- ACEのUPに対する累積的な効果を評価する.
- 既存の研究のメタ分析を行う.
主な方法:
- 151,089人の参加者を含む16件の研究が含まれています.
- 5つの英語と3つの中国語のデータベースで 経験的研究を検索しました
- 品質評価のためにAHRQとNOSを使用し,メタ分析のためにランダム/固定効果モデルを使用しました.
- 感受性/サブグループ分析と用量反応評価を実施した.
- フンネルグラフとエッガーのテストを用いて出版バイアスを調べた.
主要な成果:
- ACEはUPの確率を大幅に増加させた (OR=1. 57).
- 追加されたACEは確率を31. 8%増加させた.
- 性虐待は最も強い関連性を示した (OR=1.45).
- 地理的,経済的な格差が認められ,アフリカや低所得国での確率が高い.
結論:
- ACEは,UPと有意な線量反応関係を示しています.
- 子どもの保護,精神的健康,生殖ケアを統合した介入が推奨されています.
- 長期にわたる健康への影響を減らすには ACEの対策が不可欠です
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