ビスフェノールAは,腸内微生物に依存する胆酸代謝とCD-1マウスのTGR5/UCP1シグナル伝達経路を妨害することによって,脂肪組織の脂肪量を増加させる

Xiaobing Chen1, Jun Zou2, Ting Hong1

  • 1Department of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.

まとめ

ビスフェノールA (BPA) 曝露は腸内微生物と胆酸の代謝を乱し,肥満を引き起こす. この障害はTGR5/UCP1のシグナル伝達に影響し,エネルギー消費を減らし,脂肪量を増やす.

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