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Updated: Sep 9, 2025

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation
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M-トリフルオロメチルディフェニルデセレニドがμ-オピオイド受容体と結合する分子ダイナミクス研究:モルヒン誘発の耐性に関する計算的視点

Madiha Sardar1, Nadeem Ahmad1, Muhammad Huzaifa1

  • 1H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.

Computational biology and chemistry
|August 29, 2025
PubMed
まとめ

この研究では,TFDDがμ-オピオイド受容体 (μOR) とどのように相互作用するかを計算方法によって調べました. TFDDは安定した結合を形成し,受容体の活性に影響を与え,潜在的にオピオイド耐性および副作用を軽減します.

キーワード:
そしてダイナミック・クロス・コレレーション・マトリックス自由エネルギーによる混乱膜分子ダイナミクスモルヒンの耐性主な構成要素分析量子力学μ-オピオイド受容体

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