関連する実験動画

Updated: Sep 9, 2025

Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS
09:20

Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS

Published on: August 10, 2017

8.6K

ドナ・フロルと彼女の2人の夫:骨髄がん治療のための新しいHDAC6/AKT2阻害剤の発見

Karoline B Waitman1, Holli-Joi Martin2, Jorge A E G Carlos3

  • 1Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.

Computers in biology and medicine
|August 29, 2025
PubMed
まとめ

ハイブリッドキナーゼおよびヒストン脱酸化酵素 (HDAC) 阻害剤は,薬剤耐性血液がんとの闘いに新しいアプローチを提供します. 化合物6bと6kは強力な抗がん活性を示し,新薬発見のための予測モデルを検証しています.

キーワード:
ベンザミド血液がんヒストンデセチラーゼハイブリッド阻害剤ハイドロキサム酸キナーゼQSAR について仮想スクリーニング

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Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation11:06

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

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