関連する実験動画

Updated: Sep 9, 2025

Real-time Visualization and Analysis of Chondrocyte Injury Due to Mechanical Loading in Fully Intact Murine Cartilage Explants
08:42

Real-time Visualization and Analysis of Chondrocyte Injury Due to Mechanical Loading in Fully Intact Murine Cartilage Explants

Published on: January 7, 2019

6.9K

多様な負荷と,膝の変形中の中盤軟骨細胞におけるアポトーシスの相関

Hongjie Zhang1, Zehua Jiang2, Ziyang Liu3

  • 1Department of Orthopedics, The People's Hospital of Dehong/Kunming Medical University Affiliated Dehong Hospital, Mangshi 678400, China; Department of Spine Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin 300121, China.

Clinical biomechanics (Bristol, Avon)
|August 29, 2025
PubMed
まとめ

膝のヴァルスの角が上がると 機械的ストレスが増加し,ピエゾ1経由でコンドロシートアポトーシスを引き起こす. この経路は骨格関節炎の進行を加速し,Piezo1を軟骨変性の治療標的として特定します.

キーワード:
アポトーシス有限要素分析KV について膝関節炎ピエゾ1フォン・マイゼスのストレス

さらに関連する動画

A Non-Invasive Method for Generating the Cyclic Loading-Induced Intra-Articular Cartilage Lesion Model of the Rat Knee05:04

A Non-Invasive Method for Generating the Cyclic Loading-Induced Intra-Articular Cartilage Lesion Model of the Rat Knee

Published on: July 5, 2021

2.2K
Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants09:08

Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants

Published on: May 14, 2020

3.9K

関連する概念動画

Knee Joint01:23

Knee Joint

The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
2.2K
Deformation of Member under Multiple Loadings01:11

Deformation of Member under Multiple Loadings

When a rod is made of different materials or has various cross-sections, it must be divided into parts that meet the necessary conditions for determining the deformation. These parts are each characterized by their internal force, cross-sectional area, length, and modulus of elasticity. These parameters are then used to compute the deformation of the entire rod.
In the case of a member with a variable cross-section, the strain is not constant but depends on the position. The deformation of an...
215