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Updated: Sep 9, 2025

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
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ミトコンドリア機能障害は,JNK/p38-AP-1経路を通じた炎症反応を原始培養コンドロサイトで悪化させる

Hatsune Motonari1, Ayumu Hayashi1, Yuka Tanaka1

  • 1Department of Pharmacology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan.

International immunopharmacology
|August 29, 2025
PubMed
まとめ

ミトコンドリア機能障害は,ロテノンによって誘発され,コンドロサイトにおけるインタールイキン-1β誘発の炎症を強める. これはJNK/p38-AP-1経路を含み,骨格関節炎の潜在的治療標的を提供します.

キーワード:
ヘクソキナーゼインタールイウキン-1βミトコンドリア骨関節炎衰えること

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