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Updated: Sep 9, 2025

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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Published on: March 31, 2019

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複合的な遺伝子ロシにおける機能的規制要素の内生的な精密マッピングと優先順位付け

Ke Zhao1, Yao Zhou2, Xueqi Wang3

  • 1Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China; State Key Laboratory of Experimental Hematology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Bioinformatics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China; Center for Public Health Laboratory Testing, School of Public Health, Shandong Second Medical University, Weifang, Shandong, China.

Cell genomics
|August 29, 2025
PubMed
まとめ

複雑な特徴の遺伝的原因の多くは 非コードDNAに隠されています この研究は,遺伝子発現に影響する完全な結合不均衡 (pLD) の複数の規制要素を明らかにし,以前に隠された遺伝的メカニズムを明らかにしています.

キーワード:
CRISPRについてパートルブ=セクeQTL についてリンクの不均衡規制要素

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