関連する実験動画

Updated: Sep 9, 2025

Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay
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Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay

Published on: September 14, 2021

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切断ストレスで活性化されたMMP-2は,血管再構成中にLIMK1/コフィリン軸経由でBMSCの移動を促進する

Yuan Liang1, Jianjin Wu2, Xingjian Fang3

  • 1Department of Geriatric, 920th Hospital of PLA Joint Logistics Support Force, 212 Daguan Road, Kunming, Yunnan, China.

Microvascular research
|August 29, 2025
PubMed
まとめ

切断ストレスは,内皮細胞のマトリックス金属タンパク質-2 (MMP-2) を増加させ,LIMK1/コフィリン経路経由で骨髄メゼンキマ幹細胞 (BMSC) の移動を促進します. これはBMSC媒介による血管修復のメカニズムを明確にします.

キーワード:
BMS-3 についてBMSC について細胞の移動LIMK1/コフィリン1経路MAEC についてMMP-2 について

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