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Updated: Sep 9, 2025

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ミトコンドリア生理のメリチン誘発的調節:抗腫瘍作用を超えた

Marcos Roberto de Oliveira1

  • 1Grupo de Estudos em Neuroquímica e Neurobiologia de Moléculas Bioativas, Departamento de Química, Universidade Federal de Mato Grosso (UFMT), CEP 78060-900, Cuiaba, Mato Grosso, Brazil; Grupo de Estudos em Terapia Mitocondrial, Instituto de Ciências Básicas da Saúde (ICBS), Universidade Federal do Rio Grande do Sul (UFRGS), CEP 90035-003, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Alimentação, Nutrição e Saúde (PPGANS), Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), CEP 90035-003, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Universidade Federal do Rio Grande do Sul (UFRGS), CEP 90035-003, Porto Alegre, Rio Grande do Sul, Brazil.

Toxicon : official journal of the International Society on Toxinology
|August 29, 2025
PubMed
まとめ

ミツバチの毒ペプチドであるメリチンはミトコンドリアの機能に独特の影響を及ぼし,正常な細胞に保護効果を提供し,重要な経路を調節することによって癌細胞の細胞死を引き起こす.

キーワード:
アンチアポトシス抗酸化物質メリチンミトコンドリアミトファジー酸化性リン酸化

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