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Updated: Sep 9, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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ポマリドミド,サイクロフォスファミド,およびデキサメタソンが再発性/耐性多発性骨髄腫に対する単一センター試験

Ioannis Ntanasis-Stathopoulos1, Panagiotis Malandrakis1, Charalampos Filippatos1

  • 1Department of Clinical Therapeutics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Clinical lymphoma, myeloma & leukemia
|August 29, 2025
PubMed
まとめ

PCd療法 (ポマリドミド,サイクロフォスファミド,デキサメタゾン) は再発性/耐性多発性骨髄腫 (RRMM) の患者で有望な効果を示しています. 高リスクの細胞遺伝は結果に悪影響を及ぼし,中性不全は最も一般的な重症性であった.

キーワード:
多発性骨髄腫生き残るトリプル

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