関連する実験動画

Updated: Sep 9, 2025

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs
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Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Published on: March 2, 2018

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15q11.2 削除に関連する神経発達障害のヒトニューロンモデルにおける発達とネットワーク接続の変化

Christa W Habela1, Shiyu Liu2, Arens Taga2

  • 1Department of Neurology, Johns Hopkins University, Baltimore, MD, USA. chabela1@jh.edu.

Translational psychiatry
|August 29, 2025
PubMed
まとめ

染色体15q11.2の削除は皮質ニューロンの発達を阻害し,接続の減少とネットワーク機能の変化につながります. この遺伝的原因はニューロンの構造と活動に影響し,関連する神経発達障害を潜在的に説明します.

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