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Updated: May 5, 2026

In Vitro Aggregation Assays Using Hyperphosphorylated Tau Protein
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Published on: January 2, 2015

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シナプス変性に対するプロキシとして,CSF総tau

Carolina Soares1,2, Bruna Bellaver1, Pamela C L Ferreira1

  • 1Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

Nature communications
|August 29, 2025
PubMed
まとめ

脳脊髄液の総タウ (t-タウ) は,アルツハイマー病における神経損傷よりも,シナプス変性を示す. この発見は,t-tauが初期のシナプス変化のより敏感な指標であることを示唆しています.

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