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Updated: Sep 9, 2025

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
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A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

Published on: June 2, 2022

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NEXNは,SERCA2のSUMOylationと安定化を促すことで,血管のカルシフィケーションから保護します

Wenjie Guo1,2, Wenjing Guo1,2, Boliang Chen1,2

  • 1Department of Cardiology, Laboratory of Heart Center, Heart Center, Center for Translational Medicine Research, Zhujiang Hospital, Southern Medical University, Guangzhou, China.

Nature communications
|August 29, 2025
PubMed
まとめ

核因子X (NEXN) タンパク質の欠乏は,筋細胞のスムーズな移行を促進することによって,血管の結晶化を悪化させる. NEXNはSERCA2の機能を強化し,心血管疾患を予防する治療標的となる.

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