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Updated: Sep 9, 2025

Author Spotlight: Evaluating Biophysical Assays for Characterizing PROTACS Ternary Complexes
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Author Spotlight: Evaluating Biophysical Assays for Characterizing PROTACS Ternary Complexes

Published on: January 12, 2024

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ProtacIDを用いたPROTAC特異性と内生タンパク質相互作用の特徴化

Suman Shrestha1,2, Matthew E R Maitland1,2,3, Laili Jing1,4

  • 1Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.

Nature communications
|August 29, 2025
PubMed
まとめ

ProtacIDは,細胞内のPROTAC付近のタンパク質を識別する新しいBioID方法です. このアプローチは,PROTACの標的を検証し,PROTAC薬の開発に役立つ,分解されていないタンパク質の相互作用を発見します.

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