IL-36γ/PEDF/PPARγシグナル伝達経路は,カンジダ・アルビカンスの角膜炎において抗炎症的な役割を果たす

Chenyang Dai1, Hui Guo2, Jiayin Wu2

  • 1Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, Shandong Province, China. dcy1214@sina.com.

Scientific reports
|August 29, 2025
PubMed
まとめ

この研究では,IL-36γとピグメント上皮原産因子 (PEDF) が,Candida albicansの角膜炎において抗炎症作用を有することを明らかにした. マイクロRNA-204-5pは,IL-36γとPEDFの発現を低下させ,炎症を悪化させる.

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