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Updated: May 6, 2026

Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome
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RBM30は,STAT1転写を活性化し,肝細胞がんにおける免疫回避を駆動するためにDOT1Lを勧誘する

Hexu Han1, Chen Gong2, Yue Zhang3

  • 1Department of Gastroenterology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, Jiangsu, China. 1920716577@qq.com.

Oncogene
|August 29, 2025
PubMed
まとめ

高RBM30発現はPD- L1転写を増加させ,肝細胞癌 (HCC) の免疫回避と進行を促します. RBM30はSTAT1を調節し,PD- L1の発現を高め,腫瘍の免疫回避を促進する.

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