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Updated: Sep 9, 2025

Identification of EGFR and RAS Inhibitors using Caenorhabditis elegans
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ブファリンは,EGFR媒介のRAS-RAF-MEK-ERK経路の活性化を阻害することで,肝細胞がんの進行を抑制する

Jingwen Liu1,2, Jia Jiang1, Ju Huang1

  • 1Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.

Journal of experimental & clinical cancer research : CR
|August 29, 2025
PubMed
まとめ

ブファリン (BF) を含んだシノブファチニは,肝細胞癌 (HCC) の患者の生存率を改善すると有望である. BFはEGFR媒介のRAS/RAF/MEK/ERK経路をターゲットにすることでHCCの成長を抑制する.

キーワード:
ブファリンシノブファチーニ製薬EGFR肝細胞がんRAS/RAF/MEK/ERKについて

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