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Updated: Sep 9, 2025

A Chemical Screening Procedure for Glucocorticoid Signaling with a Zebrafish Larva Luciferase Reporter System
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A Chemical Screening Procedure for Glucocorticoid Signaling with a Zebrafish Larva Luciferase Reporter System

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低炎症応答の重症患者におけるグルココルチコイド受容体アイソフォームの細胞特異的発現と信号伝達

Georgios Poupouzas1, Nikolaos S Lotsios1, Charikleia S Vrettou1

  • 11st Department of Critical Care Medicine, Evangelismos Hospital, School of Medicine, National & Kapodistrian University of Athens, Athens, Greece.

Critical care (London, England)
|August 29, 2025
PubMed
まとめ

グルココルチコイド受容体 (GCR) のシグナリングは,重篤な疾患における免疫細胞によって異なります. ポリモルフォ核細胞 (PMN) はGCR-α/β/γの減少を示し,外周血液単核細胞 (PBMC) はGCR-PとDUSP1の上昇を調節する.

キーワード:
DUSP1 についてGCの感度GCR アイソフォームGILZ (ギルズ)免疫細胞

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